糖尿病肾病脂质代谢机制与中医药干预研究进展Research progress in mechanism of lipid metabolism in diabetic nephropathy and intervention with Chinese medicine
刘禹彤,崔成姬,王子昆,李凡,刘洪凯,李淼,张守琳
摘要(Abstract):
糖尿病肾病(DKD)被视为糖尿病最常见的微血管并发症,发病机制复杂。脂质代谢在DKD的发生发展中发挥着关键的作用。脂质蓄积和脂质代谢产物引起的氧化应激、炎症、纤维化和细胞凋亡会加重肾小球的硬化,而高脂血症除引起动脉硬化外,还能直接损伤肾脏,已被列为DKD的独立危险因素之一。通过查阅文献分析并阐述脂质代谢在DKD中作用机制,归纳并总结中医药疗法调控该机制治疗DKD的研究,为中医药治疗DKD提供新的思路与方法。
关键词(KeyWords): 脂质代谢;糖尿病肾病;发病机制;中医药
基金项目(Foundation): 吉林省自然科学基金项目(20210101201JC)
作者(Author): 刘禹彤,崔成姬,王子昆,李凡,刘洪凯,李淼,张守琳
DOI: 10.13463/j.cnki.cczyy.2025.11.023
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